Article

The cold-inducible RNA-binding protein RBM3 stabilises viral mRNA at cooler temperatures representative of the upper respiratory tract

2024-07-25

Abstract excerpt

Temperature is a critical determinant of host-pathogen interactions in the respiratory tract, where influenza A virus (IAV) has adapted to the cooler environment of the upper respiratory tract (URT) to enable efficient replication and transmission. The cold-inducible RNA-binding protein RBM3 is highly expressed in nasopharyngeal tissue and is known to stabilise mRNAs under hypothermic conditions; however, its role...

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Literature Corpus work: 92037139-40bd-57d7-968d-01b81b6a2b1d
DOI: 10.1101/2024.07.25.605104

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