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Transcriptomic signatures during normothermic liver machine perfusion correspond with graft quality and predict the early graft function

19 Sept 2024

Abstract excerpt

BACKGROUND: A better understanding of the molecular events during liver normothermic machine perfusion (NMP) is warranted to develop a data-based approach for the identification of biomarkers representative of graft quality and posttransplant outcome. We analysed the dynamic transcriptional changes during NMP and linked them to clinical and biochemical parameters. METHODS: 50 livers subjected to NMP for up to 24...

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Share to Liver physiology and pathology
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39299005
DOI: 10.1016/j.ebiom.2024.105330

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