Article

Exome-Wide Association Study of candidate pharmacogenes on DOAC haemorrhage

2024-09-10

Abstract excerpt

<h4>Background: </h4> /Objectives: Direct oral anticoagulants (DOACs) are first-line medications for stroke prevention in non-valvular atrial fibrillation (AF). However, variability in drug response poses risks of hemorrhagic or thromboembolic events. The role of genetics in determining DOAC safety is gaining attention, but evidence linking specific genetic polymorphisms to bleeding risk is lacking. Therefore, the...

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Literature Corpus work: 91dfda05-1317-5ac3-b5fb-ee0b76cf02dc
DOI: 10.20944/preprints202409.0734.v1

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