Article

A smoothed version of the Lassosum penalty for fitting integrated risk models

2021-03-10

Abstract excerpt

Polygenic risk scores are a popular means to predict the disease risk or disease susceptibility of an individual based on its genotype information. When adding other important epidemiological covariates such as age or sex, we speak of an integrated risk model. Methodological advances for fitting more accurate integrated risk models are of immediate importance to improve the precision of risk prediction, thereby po...

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Literature Corpus work: 91d5c5b4-a65e-5b27-9558-7587ba82080a
DOI: 10.1101/2021.03.09.434653

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