Article

Extracellular matrix educates a tumor macrophage phenotype found in ovarian cancer metastasis

2022-08-14

Abstract excerpt

Recent studies have shown the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and immunotherapy response. A question that remains is whether the ECM is directly educating the immune phenotypes seen in cancer. We identified a tumor-associated macrophage (TAM) population correlated with poor prognosis, interruption of the cancer immunity...

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Literature Corpus work: 91d1e80d-f971-527c-96d8-8990ced9b389
DOI: 10.1101/2022.08.11.503568

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