Article

SOCS1 expression in prostate epithelial cells is essential for tissue homeostasis and tumor suppression

2026-05-13

Abstract excerpt

Suppressor of cytokine signaling 1 (SOCS1) negative regulates inflammatory cytokine production and attenuates oncogenic growth factor signaling pathways. Reduced SOCS1 protein expression in human prostate cancer correlates with greater disease severity. To define the physiological functions of SOCS1 functions in the prostate, we conditionally ablated Socs1 in prostate epithelial cells of C57BL/6 mice. These Socs...

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Literature Corpus work: 91afc9d0-fe60-502b-a675-c56d3b72f43b
DOI: 10.64898/2026.05.09.723770

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