Article

JUN mediates senescence and immune cell recruitment to prevent prostate cancer progression

2023-11-30

Abstract excerpt

<h4>Background</h4> Prostate cancer develops through malignant transformation of the prostate epithelium in a stepwise, mutation-driven process. Although activator protein-1 transcription factors such as JUN have been implicated as potential oncogenic drivers, the molecular programs contributing to prostate cancer progression are not fully understood. <h4>Methods</h4> We analyzed JUN expression in clinical prost...

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Literature Corpus work: 82768e73-5a2f-5e9a-8ae7-e9b377a64f62
DOI: 10.1101/2023.11.29.569178

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