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Article

The senescence-associated secretory phenotype promotes benign prostatic hyperplasia.

The American journal of pathology - 1 Mar 2014

Vital Paz, Castro Patricia, Tsang Susan, Ittmann Michael

Abstract excerpt

Benign prostatic hyperplasia (BPH) is characterized by increased tissue mass in the transition zone of the prostate, which leads to obstruction of urine outflow and considerable morbidity in a majority of older men. Senescent cells accumulate in human tissues, including the prostate, with increas...

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Identifiers

PMID: 24434012
DOI: 10.1016/j.ajpath.2013.11.015
PMCID: PMC3936307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24434012-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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