Article

hMSH2 Coordinated with the Expression of E2F1 Promotes Platinum Response in Epithelial Ovarian Cancer

2022-11-01

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Previous studies have demonstrated that hMSH2 deficiency decreased platinum response in EOC. This study is to explore the underlying mechanism that regulates hMSH2 expression and drug susceptibility. <bold>Methods</bold> Transcription factors (TFs) that potentially regulate hMSH2 were predicted by bioinformatics analysis. RT-qPCR, Western blot, and luciferase assay...

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Literature Corpus work: 9184652b-ac4e-5ea4-aa63-304b03da701b
DOI: 10.21203/rs.3.rs-2188330/v1

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