Article

EZH2 Suppresses Ferroptosis in Hepatocellular Carcinoma and Reduces Sorafenib Sensitivity Through Epigenetic Regulation of TFR2

2023-09-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Sorafenib is a first-line drug, and increasing the sensitivity to sorafenib can effectively prolong the time of sorafenib resistance, which has great benefits for the treatment of patients with hepatocellular carcinoma. One of the important mechanisms of sorafenib in treating HCC is to induce cell ferroptosis. Hence, it is of great importance to investigate the...

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Literature Corpus work: c39b48d2-ab6d-5cf0-84b6-03d9bb786140
DOI: 10.21203/rs.3.rs-3343396/v1

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