Article

Spheroid culture of mesenchymal stromal cells results in morpho-rheological properties appropriate for improved microcirculation

2018-10-11

Abstract excerpt

Human bone marrow mesenchymal stromal cells (MSCs) have been used in clinical trials for the treatment of systemic inflammatory diseases due to their regenerative and immunomodulatory properties. However, intravenous administration of MSCs is hampered by cell trapping within the pulmonary capillary networks. Here, we hypothesize that traditional twodimensional (2D) plastic-adherent cell expansion fails to result i...

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Literature Corpus work: 9150e253-a51c-50d8-b0ba-96fe62f66688
DOI: 10.1101/440966

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