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Current perspectives on the dynamic culture of mesenchymal stromal/stem cell spheroids

31 Dec 2024

Abstract excerpt

Mesenchymal stromal/stem cells (MSCs) are promising candidates for regenerative medicine owing to their self-renewal properties, multilineage differentiation, immunomodulatory effects, and angiogenic potential. MSC spheroids fabricated by 3D culture have recently shown enhanced therapeutic potential. MSC spheroids create a specialized niche with tight cell-cell and cell-extracellular matrix interactions,...

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PMID: 39737878
DOI: 10.1093/stcltm/szae093

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