Article

Functional identification of microRNAs counteracting cellular senescence

2017-01-01

Abstract excerpt

Cellular senescence is a process closely linked to organismal ageing, and clearance of senescent cells has been shown to revert aspects of the ageing phenotype. We sought to identify miRNAs able to counteract replicative senescence at the cellular level, and investigate their effect in vivo. A library of 879 human miRNAs mimics was used for a high throughput screen using high content microscopy to search for miRNA...

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Literature Corpus work: 9148a327-f85d-5cf5-ba2d-9dcac7a8dd9f
DOI: 10.21954/ou.ro.0000c01f

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