MicroRNA and Senescence: The Senectome, Integration and Distributed Control

Abstract excerpt

Cellular senescence has attracted renewed interest in recent years in light of the realization that cancer cells are susceptible to senescence-like responses to stress including exposure to chemotherapeutic agents. Therefore, senescence is viewed as a potentially important target in cancer therapy. However, translation of senescence therapeutics will rely on identifying appropriate marker panels for assessing...

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