Article

Viral antigen mismatch affects antiviral T-cell response and may impair immunotherapeutic efficacy against ATL

2024-01-29

Abstract excerpt

Human T-cell leukemia virus type 1 (HTLV-1) has the potential to transform primary CD4 + T cells in vitro within a short time; however, the majority of infected individuals maintain an asymptomatic and disease-free condition, suggesting the existence of an equilibrium between the proliferation of infected cells and host immunity. The decline in anti-viral immunity contributes to the transformation of the infecte...

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Literature Corpus work: 9130a643-9774-5989-b53c-c3cb813f2c85
DOI: 10.1101/2024.01.25.576615

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