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Article

APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo.

Journal of virology - 1 Jul 2010

Fan Jun, Ma Guangyong, Nosaka Kisato, Tanabe Junko, Satou Yorifumi, Koito Atsushi, Wain-Hobson Simon, Vartanian Jean-Pierre, Matsuoka Masao

Abstract excerpt

Human T-cell leukemia virus type 1 (HTLV-1) induces cell proliferation after infection, leading to efficient transmission by cell-to-cell contact. After a long latent period, a fraction of carriers develop adult T-cell leukemia (ATL). Genetic changes in the tax gene in ATL cells were reported in about 10% of ATL cases. To determine genetic changes that may occur throughout the provirus, we determined the entire...

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Identifiers

PMID: 20463074
DOI: 10.1128/JVI.02239-09
PMCID: PMC2898234

Genes

HBZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo.PMID 20463074Read ↗

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