Article

Combined Treatment with Dopamine Receptor Antagonists and Radiation Creates a Metabolic Vulnerability in Mouse Models of Glioblastoma

2020-01-14

Abstract excerpt

<h4>Background</h4> Glioblastoma is the deadliest brain tumor in adults and the standard-of-care consists of surgery followed by radiation and treatment with temozolomide. Overall survival times for patients suffering from glioblastoma are unacceptably low indicating an unmet need for novel treatment options. <h4>Methods</h4> Using patient-derived glioblastoma lines and mouse models of glioblastoma we test the e...

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Identifiers and source

Literature Corpus work: 912315ed-dc9b-5f94-bde1-c94f9f3fda29
DOI: 10.1101/2020.01.13.905380

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