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Article

Distinct Control of histone H1 expression within the Histone Locus body by CRAMP1

2025-01-08

Abstract excerpt

Proper histone gene expression is critical to cell viability and maintaining genomic integrity. Multiple histone genes organized into three genomic loci encode for replication coupled core and linker histones. Histone gene expression and transcript processing is orchestrated in the histone locus body (HLB) within the nucleus. We identified human CRAMP1 as a selective regulator of linker histone H1 expression. CRAM...

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Literature Corpus work
910f8cab-b5b3-552a-b89e-da0946e9696c
DOI
10.1101/2025.01.07.631602
Open publication

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Distinct Control of histone H1 expression within the Histone Locus body by CRAMP1DOI 10.1101/2025.01.07.631602
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