Article

MTALTND4, a second protein coded by <i>nd4</i> impacts mitochondrial bioenergetics

2022-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Recent evidence suggests that the coding potential of the mitogenome is underestimated. We found a downstream alternative ATG initiation codon in the +3 reading frame of the human mitochondrial nd4 gene. This newly characterized alternative open reading frame (altORF) encodes a 99-amino acids long polypeptide, MTALTND4, which is conserved in primates. This small protein is localized in mitochon...

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Literature Corpus work: 9104c737-58ba-5fbb-920d-f8d6da23a5a6
DOI: 10.1101/2022.04.28.489924

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