Article

BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

2020-02-01

Abstract excerpt

The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly expanding the known proteome at the lower end of the size distribution 1,2 . Here, we show that the mitochondria proteome is enriched for proteins smaller than 100 a.a. (defined as SEPs). Using a mitochondrial prediction and validation pipeline for small open-reading-frame (sORF)-encoded peptides (SEPs), we report the discovery of...

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Literature Corpus work: 0d0d8c7f-def7-52ae-94ec-9373228bd897
DOI: 10.1101/2020.01.31.926402

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