Article
Roles of MT-ND1 in Cancer.
Current medical science - 1 Oct 2023
Xu Yi-Chun, Su Jun, Zhou Jia-Jing, Yuan Qing, Han Jun-Song
Abstract excerpt
The energy shift toward glycolysis is one of the hallmarks of cancer. Complex I is a vital enzyme complex necessary for oxidative phosphorylation. The mitochondrially encoded NADH: ubiquinone oxidoreductase core subunit 1 (MT-ND1) is the largest subunit coded by mitochondria of complex I. The present study summarizes the structure and biological function of MT-ND1. From databases and literature, the expressions...
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