Article

Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease

2019-10-01

Abstract excerpt

<h4>SUMMARY</h4> To study the molecular mechanisms driving the pathogenesis and identify novel therapeutic targets of late onset Alzheimer’s Disease (LOAD), we performed an integrative network analysis of whole-genome DNA and RNA sequencing profiling of four cortical areas, including the parahippocampal gyrus, across 364 donors spanning the full spectrum of LOAD-related cognitive and neuropathological disease sev...

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Literature Corpus work: 90e5d3b6-7675-5efe-9728-8fc637d6b248
DOI: 10.1101/788323

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