Article

Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p mediated inhibition of Notch signaling pathway

2022-05-31

Abstract excerpt

<title>Abstract</title> <p>Background Mesenchymal stem cells (MSCs) are considered to be a potential therapeutic tool for liver fibrosis. Inhibiting the activation of hepatic stellate cells (HSCs) and protecting hepatocytes are important mechanisms for the anti-fibrotic effect of MSCs. However, how MSCs inhibit liver fibrosis by regulating the expression of microRNAs (miRNAs) has not been fully clarified. Method...

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Literature Corpus work: 4795f0ef-4449-5eb4-b4f2-f977aac6a4a5
DOI: 10.21203/rs.3.rs-1666306/v1

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