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Article

Exosomes derived from gastric cancer cells promote phenotypic transformation of hepatic stellate cells and affect the malignant behavior of gastric cancer cells.

Journal of cancer research and therapeutics - 1 Aug 2024

Zhang Donghuan, Luo Qiong, Xiao Lirong, Chen Xiangqi, Yang Sheng, Zhang Suyun

Abstract excerpt

OBJECTIVE: This study aimed to evaluate the effect of exosomes derived from gastric cancer cells on the phenotypic transformation of hepatic stellate cells (HSCs) and the effect of HSC activation on the malignant behavior of gastric cancer cells, including its molecular mechanism. METHODS: Exosomes derived from the human gastric adenocarcinoma cell line AGS were extracted and purified by polymer precipitation and...

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Identifiers

PMID: 39206977
DOI: 10.4103/jcrt.jcrt_749_23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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