Article

The structural characterisation of two DNA protectants during stress : the tandem RRM domains of mouse TDP-43 and E. coli DPS

2013-01-01

Abstract excerpt

TAR DNA Binding protein (TDP-43) is a member of the heterogeneous nuclear ribonucleoprotein family with crucial splicing, transport and regulatory function of genetic material inside mammalian cells. Unfortunately, TDP-43 positive cytoplasmic aggregates occurring with post-translational modifications are a common hallmark in neurodegenerative diseases observed in Alzheimer’s, Parkinson’s, amyotrophic lateral scler...

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Literature Corpus work: 90ce60a3-87dc-5abf-a7b9-27c6772166e4
DOI: 10.17638/00016713

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