Article

Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions

2024-09-12

Abstract excerpt

MicroRNAs are essential post-transcriptional regulators of gene expression and involved in many biological processes; however, our understanding of their genetic regulation and role in brain illnesses is limited. Here, we mapped brain microRNA expression quantitative trait loci (miR-QTLs) using genome-wide small RNA sequencing profiles from dorsolateral prefrontal cortex (dlPFC) samples of 604 older adult donors o...

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Literature Corpus work: 08dd4497-571c-5dd6-9a69-e7d023617ca5
DOI: 10.1101/2024.09.10.610174

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