Article

Virus-host interaction: investigating novel transcription factors involved in coupling HPV life cycle and epithelial differentiation

2024-06-22

Abstract excerpt

High-risk human papillomavirus (HPV) causes almost all cervical cancer, and HPV-18 is the second most prevalent type. The HPV life cycle is intimately associated with the epithelial differentiation program, and the repertoire of cellular transcription factors (TFs) has a crucial role in coordinating viral gene expression across epithelial layers. We aimed to identify host TFs involved in the virus differentiation-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 908e65db-625c-59c1-85ab-b69cf17bee87
DOI: 10.1101/2024.06.21.599992

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Virus-host interaction: investigating novel transcription factors involved in coupling HPV life cycle and epithelial differentiationDOI 10.1101/2024.06.21.599992Read

E6AP is important for HPV E6’s role in regulating epithelial homeostasis and its loss impairs keratinocyte commitment to differentiationSemantic proximity Read

CCCTC-Binding Factor Recruitment to the Early Region of the Human Papillomavirus 18 Genome Regulates Viral Oncogene ExpressionSemantic proximity Read

Regulation of HPV transcriptionSemantic proximity Read

Identification of novel cellular transcription factors that regulate early promoters of human papillomavirus types 18 and 16.Semantic proximity Read

HPV as a Molecular Hacker: How the Virus Hijacks Transcription Factors to Trigger CancerSemantic proximity Read

Regulation of human papillomavirus type 31 gene expression during the differentiation-dependent life cycle through histone modifications and transcription factor bindingSemantic proximity Read

Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcriptionSemantic proximity Read

Regulation and Deregulation of Viral Gene Expression During High-Risk HPV InfectionSemantic proximity Read

RNA Binding Proteins that Control Human Papillomavirus Gene ExpressionSemantic proximity Read

HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional RegulationSemantic proximity Read

Differentiation-Dependent Proximity Proteomics Identifies Novel Host Factors Linked to HPV16 E2 FunctionSemantic proximity Read

The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune responseSemantic proximity Read