Article
The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune response
20 Sept 2019
Abstract excerpt
The Human Papillomavirus (HPV) E1 protein is the only viral protein with enzymatic activity. The main known function of this protein is the regulation of the viral DNA replication. Nevertheless, it has been demonstrated that the ablation of HPV18 E1 mRNA in HeLa cells promotes a deregulation of several genes, particularly those involved in host defense mechanisms against viral infections; however, the specific...
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