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RNA Binding Proteins that Control Human Papillomavirus Gene Expression

5 May 2015

Abstract excerpt

The human papillomavirus (HPV) life cycle is strictly linked to the differentiation program of the infected mucosal epithelial cell. In the basal and lower levels of the epithelium, early genes coding for pro-mitotic proteins and viral replication factors are expressed, while terminal cell differentiation is required for activation of late gene expression and production of viral particles at the very top of the...

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PMID: 25950509
DOI: 10.3390/biom5020758

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