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Article

Potential roles of mediator Complex Subunit 13 in Cardiac Diseases

16 Dec 2020

Abstract excerpt

Mediator complex subunit 13 (MED13, previously known as THRAP1 and TRAP240) is a subunit of the cyclin-dependent kinase 8 (CDK8) kinase module in the eukaryotic mediator complex. MED13 has been known to play critical roles in cell cycle, development, and growth. The purpose of this review is to comprehensively discuss its newly identified potential roles in myocardial energy metabolism and non-metabolic...

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PMID: 33390853
DOI: 10.7150/ijbs.52290

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