Article

Relative Contribution of Amyloid-β Plaque Associated and Plaque Distant Microglia to Alzheimer’S Disease (AD) Progression

2021-12-23

Abstract excerpt

<h4>Background: </h4> Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD). In parallel, a series of studies showed that, under both homeostatic and pathological conditions, microglia are a heterogeneous cell population. In AD, amyloid-b (Ab) plaque-associated microglia (PAM) display a clearly distinct phenotype compared to plaque-...

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Literature Corpus work: 904033c7-7440-55bd-a073-ac40fb3e7985
DOI: 10.21203/rs.3.rs-876995/v2

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