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Linc RNA ‐p21 suppresses development of human prostate cancer through inhibition of PKM 2

9 Oct 2017

Abstract excerpt

OBJECTIVES: Previously, we found that long intergenic non-coding RNA-p21 (lincRNA-p21) inhibited the development of human prostate cancer. However, the underlying molecular mechanisms are poorly understood. Here, we attempted to investigate the downstream targets of lincRNA-p21 in prostate cancer. MATERIALS AND METHODS: Expression of lincRNA-p21 and PKM2 was determined by qRT-PCR and Western blot. Lentivirus...

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PMID: 28994148
DOI: 10.1111/cpr.12395

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