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Article

Platelets disrupt vasculogenic mimicry by cancer cells

3 Apr 2020

Abstract excerpt

Abstract Tumour vasculature supports the growth and progression of solid cancers with both angiogenesis (endothelial cell proliferation) and vasculogenic mimicry (VM, the formation of vascular structures by cancer cells themselves) predictors of poor patient outcomes. Increased circulating platelet counts also predict poor outcome for cancer patients but the influence of platelets on tumour vasculature is...

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PMID: 32246008
DOI: 10.1038/s41598-020-62648-x

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