Article

Impaired ovarian development in a zebrafish <i>fmr1</i> knockout model

2024-02-10

Abstract excerpt

Fragile X syndrome (FXS) is an inherited neurodevelopmental disorder and the leading genetic cause of autism spectrum disorders. FXS is caused by loss of function mutations in Fragile X mental retardation protein (FMRP), an RNA binding protein that is known to regulate translation of its target mRNAs, predominantly in the brain and gonads. The molecular mechanisms connecting FMRP function to neurodevelopmental phe...

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Literature Corpus work: 90064b0f-5971-5e04-a4c0-956d6ebd3388
DOI: 10.1101/2024.02.10.579749

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