Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation and characterization of FMR1 knockout zebrafish.

PloS one - 19 Nov 2009

den Broeder Marjo J, van der Linde Herma, Brouwer Judith R, Oostra Ben A, Willemsen Rob, Ketting René F

Abstract excerpt

Fragile X syndrome (FXS) is one of the most common known causes of inherited mental retardation. The gene mutated in FXS is named FMR1, and is well conserved from human to Drosophila. In order to generate a genetic tool to study FMR1 function during vertebrate development, we generated two mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Brain
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Neurons

Share to RNA-Binding Proteins

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19936290
DOI: 10.1371/journal.pone.0007910
PMCID: PMC2774943

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19936290-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation and characterization of FMR1 knockout zebrafish.PMID 19936290Read ↗

Hyperactivity, Memory Defects, and Craniofacial Abnormalities in Zebrafish fmr1 Mutant Larvae.Semantic proximity Read ↗

Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium.Semantic proximity Read ↗

Knockout mouse model for Fxr2: a model for mental retardation.Semantic proximity Read ↗

Impaired ovarian development in a zebrafish <i>fmr1</i> knockout modelSemantic proximity Read ↗

Engineering an <i>fgfr4</i> knockout zebrafish to study its role in development and diseaseSemantic proximity Read ↗

An extensive de novo deletion removing FMR1 in a patient with mental retardation and the fragile X syndrome phenotype.Semantic proximity Read ↗

Behavioral and synaptic circuit features in a zebrafish model of fragile X syndrome.Semantic proximity Read ↗

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.Semantic proximity Read ↗

Loss of FMRP affects ovarian development and behaviour through multiple pathways in a zebrafish model of fragile X syndrome.Semantic proximity Read ↗

FMR1 gene and fragile X syndrome.Semantic proximity Read ↗

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.Semantic proximity Read ↗

Morphants: a new systematic vertebrate functional genomics approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.