Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feeding

Abstract excerpt

Abstract Background The host–microbiota interaction plays a crucial role in maintaining homeostasis and disease susceptibility, and microbial tryptophan metabolites are potent modulators of host physiology. However, whether and how these metabolites mediate host–microbiota interactions, particularly in terms of inter-microbial communication, remains unclear. Results Here, we have demonstrated that indole-3-lactic...

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• Share to Clostridium difficile and Clostridium perfringens research
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