Microbial modulation of tryptophan metabolism links gut microbiota to disease and its treatment

Abstract excerpt

Emerging studies have demonstrated that tryptophan (Trp) metabolism plays a critical role in maintaining intestinal and systemic homeostasis. Trp metabolism is involved in diseases such as metabolic syndrome, gastrointestinal cancers, neurological disorders, and viral diseases. The gut microbiota is crucial for regulating Trp metabolism, thereby influencing host health. Conversely, Trp metabolism can also...

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