Article
Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.
PloS one - 1 Jan 2014
Furukawa Hiroshi, Kawasaki Aya, Oka Shomi, Ito Ikue, Shimada Kota, Sugii Shoji, Hashimoto Atsushi, Komiya Akiko, Fukui Naoshi, Kondo Yuya, Ito Satoshi, Hayashi Taichi, Matsumoto Isao, Kusaoi Makio, Amano Hirofumi, Nagai Tatsuo, Hirohata Shunsei, Setoguchi Keigo, Kono Hajime, Okamoto Akira, Chiba Noriyuki, Suematsu Eiichi, Katayama Masao, Migita Kiyoshi, Suda Akiko, Ohno Shigeru, Hashimoto Hiroshi, Takasaki Yoshinari, Sumida Takayuki, Nagaoka Shouhei, Tsuchiya Naoyuki, Tohma Shigeto
Abstract excerpt
Many studies on associations between human leukocyte antigen (HLA) allele frequencies and susceptibility to systemic lupus erythematosus (SLE) have been performed. However, few protective associations with HLA-DRB1 alleles have been reported. Here, we sought protective, as well as predispositional, alleles of HLA-DRB1 in Japanese SLE patients. An association study was conducted for HLA-DRB1 in Japanese SLE...
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