Article

LPS induces GFAT2 expression to promote O-GlcNAcylation and attenuate inflammation in macrophages

2020-03-23

Abstract excerpt

O-GlcNAc glycosylation is a reversible post-translational modification that regulates the activity of intracellular proteins according to glucose availability and its metabolism through the hexosamine biosynthesis pathway (HBP). This modification has been involved in the regulation of various immune cell types, including macrophages. However, little is known concerning the mechanisms that regulate protein O-GlcNAc...

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Literature Corpus work: 8f567c87-19da-5bb3-920b-d66077812242
DOI: 10.1101/2020.03.22.002303

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