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Cell-specific isotope labeling identifies <i>myo</i> -inositol transfer between neurons and oligodendroglia to support myelin repair

2026-03-22

Abstract excerpt

Neurons and glial cells are biochemically coupled through the exchange of nutrients, but our knowledge of which metabolites are transferred between them remains limited due to technical challenges. Here, we introduce a strategy to label specific cell types with isotopic tracers so that metabolite transfer can be measured directly in the intact brain. By engineering neurons in mice to metabolize 13 C-labeled cello...

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Literature Corpus work
8f18b6fe-8be9-57e7-85a1-1f3ed68127e7
DOI
10.64898/2026.03.19.712965
Open publication

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Cell-specific isotope labeling identifies <i>myo</i> -inositol transfer between neurons and oligodendroglia to support myelin repairDOI 10.64898/2026.03.19.712965
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