Imaging Cellular Metabolic Rewiring with SuMMIT-SRS

Abstract excerpt

<h4>Summary</h4> Cells dynamically rewire their metabolic pathways in response to physiological and pathological cues. Such plasticity is particularly critical in neurons, stem cells, cancer cells, and immune cells, where biosynthetic demands can shift rapidly. However, current metabolic imaging techniques using isotope labeling typically track only one metabolite at a time, limiting their ability to capture the...

Topics

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• Autophagy
• Biosynthetic Pathways
• Fatty Acids
• Lipid Metabolism
• Neoplasms
• Phenotype
• Single-Cell Analysis
• Spectrum Analysis, Raman

Identifiers and source

Literature Corpus work

a1a403d1-e326-5579-bde5-6d02e57fd044

DOI

10.1101/2025.10.10.681769