Article

Characterization of betacoronavirus HKU-1 and OC43 internal proteins using a prototypic coronavirus

2025-04-24

Abstract excerpt

Coronaviruses express a repertoire of accessory proteins for evading host immune responses. A small internal (I) accessory protein is expressed by the genus Betacoronavirus . Previous studies reported that the I proteins of SARS-CoV, MERS-CoV and SARS-CoV-2 inhibit type I interferon (IFN-I) expression through distinct mechanisms and have different roles in pathogenesis. Human coronaviruses (hCoV) HKU1 and OC43 ar...

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Literature Corpus work: 8f14f3d1-7781-5dce-a7b9-fdca2709657e
DOI: 10.1101/2025.04.23.650176

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