H19 gene polymorphisms and Wilms tumor risk in Chinese children: a four-center case-control study

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Wilms tumor is the most common pediatric renal cancer. However, genetic bases behind Wilms tumor remain largely unknown.<italic> H19 </italic>is a critical maternally imprinted gene. Previous studies indicated that nucleotide polymorphisms (SNPs) in the <italic>H19 </italic>can modify the risk of several human malignancies. Epigenetic errors at the <italic>H19</i...

Topics

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• Child, Preschool
• China
• Genes, Modifier
• Infant
• Neoplasms
• Polymorphism, Single Nucleotide
• RNA, Long Noncoding
• Wilms Tumor

Identifiers and source

Literature Corpus work

8eed6a00-1eaa-554d-9915-3cbe138b4150

DOI

10.21203/rs.2.23509/v2