Article
Genetic variants in lncRNA H19 are associated with the risk of bladder cancer in a Chinese population.
Mutagenesis - 1 Sept 2016
Hua Qiuhan, Lv Xu, Gu Xiang, Chen Yaoyao, Chu Haiyan, Du Mulong, Gong Weida, Wang Meilin, Zhang Zhengdong
Abstract excerpt
The long non-coding RNA (lncRNA) H19 as an imprinted gene transcribed from only the maternal allele has the vital role in carcinogenesis. Aberrant H19 expression is involved in bladder cancer development. In this study, we explored the association between single nucleotide polymorphisms (SNPs) in H19 and bladder cancer risk. Four tagging SNPs (tagSNPs) were selected from the 1000 Genomes Project database. In...
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