Article
Polymorphisms in the H19 gene and the risk of bladder cancer.
European urology - 1 Nov 2008
Verhaegh Gerald W, Verkleij Linda, Vermeulen Sita H H M, den Heijer Martin, Witjes J Alfred, Kiemeney Lambertus A
Abstract excerpt
OBJECTIVES: H19 is an imprinted gene coding for an oncofetal RNA that is down-regulated postnatally. Reactivation of the H19 gene has been observed in bladder tumors, and H19 expression has been associated with early recurrence of disease. In this study we examined whether sequence variants within the H19 gene are associated with the risk of developing bladder cancer. METHODS: Five tagging single nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
