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A Dual Target-Directed Single Domain-Based Fusion Protein Against Interleukin-6 Receptor Decelerate Experimental Arthritis Progression Via Modulating JNK Expression

2021-02-19

Abstract excerpt

The currently used anti-cytokine therapeutic antibodies cannot selectively neutralize pathogenic cytokine signalling that cause collateral damage to protective signalling cascades. The single domain chain firstly discovered in Camelidae displays fully functional ability in antigen-binding against variable targets, which has been seemed as attractive candidates for the next-generation biologic drug study. In this s...

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Literature Corpus work
8ed97fa3-2022-5568-973a-3104aac6e603
DOI
10.21203/rs.3.rs-212152/v1
Open publication

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A Dual Target-Directed Single Domain-Based Fusion Protein Against Interleukin-6 Receptor Decelerate Experimental Arthritis Progression Via Modulating JNK ExpressionDOI 10.21203/rs.3.rs-212152/v1
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