Fourth-generation chimeric antigen receptor T-cell therapy is tolerable and efficacious in treatment-resistant rheumatoid arthritis

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by symmetric synovial inflammation leading to progressive disability. 1 Treatment of RA has been revolutionized by the development of monoclonal antibodies against cytokines (e.g., tumor necrosis factor-α (TNFα) and interleukin-6 (IL-6)) as well as B-cells (e.g., CD20-targeted antibody rituximab), resulting in better disease control. 2...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biosimilars and Bioanalytical Methods
• Share to CAR-T cell therapy research
• Share to Integrated Circuits and Semiconductor Failure Analysis