Article

Tumor Suppressor Immune Gene Therapy to Reverse Immunotherapy Resistance

2021-01-02

Abstract excerpt

<h4>Background</h4> While immune checkpoint inhibitors are becoming a standard of care for multiple types of cancer, the majority of patients do not respond to this form of immunotherapy. New approaches are required overcome resistance to immunotherapies. <h4>Methods</h4> We investigated the effects of adenoviral p53 (Ad-p53) gene therapy in combination with immune checkpoint inhibitors and selective IL2 or IL15 C...

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Literature Corpus work: 8ecfd303-9b09-536a-b3e4-9c3236347d2d
DOI: 10.1101/2020.12.27.20248913

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