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Is <i>mda-7/IL-24</i> a “Magic Bullet” for Cancer?

15 Nov 2005

Abstract excerpt

The "holy grail" of cancer therapy is to identify and exploit genetic elements and signal transduction pathways capable of selectively destroying tumor cells without eliciting harmful effects in normal cells or tissues. To achieve this objective, subtraction hybridization was combined with a "differentiation therapy" model of cancer in which human melanoma cells were induced to revert to a more "normal" state,...

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PMID: 16287994
DOI: 10.1158/0008-5472.can-05-3127

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