Article
Whole-genome sequencing reveals the genetic mechanisms of domestication in classical inbred mice.
Genome biology - 26 Sept 2022
Liu Ming, Yu Caixia, Zhang Zhichao, Song Mingjing, Sun Xiuping, Piálek Jaroslav, Jacob Jens, Lu Jiqi, Cong Lin, Zhang Hongmao, Wang Yong, Li Guoliang, Feng Zhiyong, Du Zhenglin, Wang Meng, Wan Xinru, Wang Dawei, Wang Yan-Ling, Li Hongjun, Wang Zuoxin, Zhang Bing, Zhang Zhibin
Abstract excerpt
BACKGROUND: The laboratory mouse was domesticated from the wild house mouse. Understanding the genetics underlying domestication in laboratory mice, especially in the widely used classical inbred mice, is vital for studies using mouse models. However, the genetic mechanism of laboratory mouse domestication remains unknown due to lack of adequate genomic sequences of wild mice. RESULTS: We analyze the genetic...
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